قطع الكبد الجراحي للنقائل الورمية من سرطانات القولون و المستقيم

Authors

  • عماد أيوب

Abstract

شملت الدراسة 11 مريضاً بنسبة 63.6% للإناث ومتوسط الأعمار 55.4 سنة. لقد توضع الورم البدئي في المستقيم في 36.4% و تم تشخيص وجود النقيلة او النقائل الكبدية بشكل متزامن مع تشخيص الورم  البدئي في 4  حالات و بنسبة 36.4% بينما تم حدوث النقائل الكبدية بشكل متأخر في 63.6% من الحالات. وجدت النقيلة الوحيدة عند 72.7% بينما شكلت النقائل المتعددة نسبة 27.3%. و كان قطر النقيلة اقل من 5 سم في 5 حالات و بنسبة 45.4% و كانت اكبر او يساوي 5 سم في 54.6% من الحالات. تم اجراء قطع كبد للنقيلة بشكل متزامن مع استئصال الورم البدئي الموجود في القولون في حالة واحدة فقط و كانت نقيلة وحيدة و بنسبة 9.1% من الحالات. شكل قطع الكبد لقطعة او قطعتين كبديتين الاجراء الجراحي الاكثر تواترا و بنسبة 45.4% من الحالات في حين تم اجراء قطع فص كبدي ايمن تام في حالة واحدة و كذلك قطع فص كبدي ايسر تام ايضا في حالة وحيدة. حدث تجمع صفراوي تالي للجراحة في حالة واحدة و لم تستدعي التداخل الجراحي. و حدث النزف الدموي بشكل فعال في حالة واحدة وحدث الناسور الصفراوي في حالتين و لم تحدث أية وفاة خلال الاشهر الثلاثة الاولى التالية للجراحة. معدل البقيا للسنة الاولى كانت بنسبة 100% اما البقيا لمدة بين 3 الى 5 سنوات فكانت 45% و في حالة واحدة تجاوزت البقيا 5 سنوات

Introduction: Liver surgery is a relatively recent and relatively major complex surgery, due to the anatomical and histological specialty of the liver

Objective of the research: To evaluate the results of the cases of liver metastases from colorectal carcinoma from November 2010 until the end of April 2017.The study included 11 patients with 63,4% of females and average age of 55,4 years.

The primary tumor was located in the rectum at 36.4%. in 4 cases (36.4%) was the livermetastases as a synchron with the main tumor while the metachron metastases was in 63.6% of cases. The single metastases was found at 72.7% while the multiple metastases accounted for 27.3%. The transfusion diameter was less than 5 cm in 5 cases and 45.4% and it was larger or equal to 5 cm in 54.6% of all the cases. The liver resection for Hepatocellular lesions were performed concurrently with primary tumor resection in the colon in only one case and the metastases was a single and 9.1% of the cases. The most common surgical procedure was segment resection in 45.4% of all the cases. The left or right hemi hepatectomy was in two cases, 8.7% None of the patients had any complications which requiring a reoperation. Bleeding occurred in one case such as the Bilioma in one case and Biliary fistula occurred in two cases. The survival time for the first year was 100% and 45% for (3-5) years and in one case till now mor than 5 years.

References

A Chiappa , E Bertani , R Biffi , U Pace , G Viale , G Pruneri , G Zampino , N Fazio , F Orsi , G Bonomo , L Monfardini , P Della Vigna and B Andreoni. Resection of colorectal liver metastases following neoadjuvant chemotherapy.

ecancer 2007, 1:58 DOI: 10.3332/ecancer.2008.58.

Matteo Donadon, Dario Ribero, Gareth Morris-Stiff, Eddie K. Abdalla, and Jean-Nicolas Vauthey. New Paradigm in the Management of Liver-Only Metastases From Colorectal Cancer Gastrointest Cancer Res 2007 1:20–27. © 2007.

Kristen Little, MSPA, PA-C.Is a surgical CURE in the future for colorectal cancer liver metastasis. International Journal of Surgery Oncology (2017) 2:e34

Sylvain Manfredi, MD, Coˆme Lepage, MD, Cyril Hatem, MD, Olivier Coatmeur, MD,Jean Faivre, PhD, and Anne-Marie Bouvier, PhD. Epidemiology and Management of Liver Metastases From Colorectal Cancer. Annals of Surgery 2006 Volume 244, Number 2, August 2006

John S. Bolton, MD, and George M. Fuhrman, MD. Survival After Resection of Multiple Bilobar Hepatic Metastases From Colorectal Carcinoma. ANNALS OF SURGERY 2000. Vol. 231, No. 5, 743–751

J N Primrose. Treatment of colorectal metastases: surgery, cryotherapy,or radiofrequency ablation. Gut 2002;50:1–5

Yuman Fong, MD. Surgical Therapy of Hepatic Colorectal Metastasis.CA Cancer J Clin 1999;49:231-255

Rene´ Adam MD, PhD, Ge´rard Pascal, MD, Daniel Azoulay, MD, PhD, Kuniya Tanaka, MD,Denis Castaing, MD, and Henri Bismuth, MD, FACS Hon. Liver Resection for Colorectal Metastases The Third Hepatectomy. Annals of Surgery 2003 • Volume 238, Number 6, December 2003

SR Bramhall, U Gur, C Coldham, BK Gunson, AD Mayer, P McMaster, D Candinas, JAC Buckels, DF Mirza.Liver resection for colorectal metastases. Ann R Coll Surg Engl 2003; 85: 334–339

G. Fusai B.R. Davidson. Strategies to Increase the Resectabilityof Liver Metastases from ColorectalCancer. Dig Surg 2003;20:481–496

AG Heriot, J Reynolds, CG Marks, N Karanjia. Hepatic resection for colorectal metastases – a national Perspective. Ann R Coll Surg Engl 2004; 86: 420–424

Timothy M. Pawlik, MD, MPH,* Charles R. Scoggins, MD,* Daria Zorzi, MD,*Eddie K. Abdalla, MD,* Axel Andres, MD,_ Cathy Eng, MD,† Steven A. Curley, MD,*Evelyne M. Loyer, MD,‡ Andrea Muratore, MD,§ Gilles Mentha, MD,_Lorenzo Capussotti, MD,§ and Jean-Nicolas Vauthey, MD*. Effect of Surgical Margin Status on Survival and Site ofRecurrence After Hepatic Resection forColorectal Metastases. Annals of Surgery 2005 • Volume 241, Number 5, May 2005

. PC Simmonds1, JN Primrose*,2, JL Colquitt1, OJ Garden3, GJ Poston4 and M Rees5. Surgical resection of hepatic metastases from colorectal cancer: A systematic review of published studies. British Journal of Cancer (2006) 94, 982 – 999

S Bhattacharjya1, R Aggarwal1 and BR Davidson. Intensive follow-up after liver resection for colorectal liver metastases: results of combined serial tumour marker estimations and computed tomography of the chest and abdomen – a. British Journal of Cancer (2006) 95, 21 – 26

Weitz J, Blumgart LH, Fong Y, Jarnagin WR, D'Angelica M, Harrison LE, DeMatteo RP. Partial hepatectomy for metastases from noncolorectal, nonneuroendocrine carcinoma. Annals of Surgery Vol 241 No. 2, 2015, 69-76.

Downloads

Published

2018-12-27

How to Cite

1.
أيوب ع. قطع الكبد الجراحي للنقائل الورمية من سرطانات القولون و المستقيم. Tuj-hlth [Internet]. 2018Dec.27 [cited 2025Jul.8];40(6). Available from: http://www.journal.tishreen.edu.sy/index.php/hlthscnc/article/view/5791

Issue

Vol. 40 No. 6 (2018): العلوم الصحية

Section

Articles

License

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.

The authors retain the copyright and grant the right to publish in the magazine for the first time with the transfer of the commercial right to Tishreen University Journal for Research and Scientific Studies - Health Sciences Series

 Under a CC BY- NC-SA 04 license that allows others to share the work with of the work's authorship and initial publication in this journal. Authors can use a copy of their articles in their scientific activity, and on their scientific websites, provided that the place of publication is indicted in  Tishreen University Journal for Research and Scientific Studies - Health Sciences Series   .  The Readers have the right to send, print and subscribe to the initial version of the article, and the title of  Tishreen University Journal for Research and Scientific Studies - Health Sciences Series  Publisher

journal uses a CC BY-NC-SA license which mean

You are free to:

  • Adapt — remix, transform, and build upon the material
  •  
  • The licensor cannot revoke these freedoms as long as you follow the license terms.

 

  • Attribution — You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use.
  • NonCommercial — You may not use the material for commercial purposes.
  • ShareAlike — If you remix, transform, or build upon the material, you must distribute your contributions under the same license as the original.
  • No additional restrictions — You may not apply legal terms or technological measures that legally restrict others from doing anything the license permits.